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At enrollment, patients had to be at least 18 years of age, have a hemoglobin level of less than 11.
Five categories -A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
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Discontinue erythropoietin following completion of chemotherapy.
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PROCRIT t½ among adult patients above or below 65 years of age.
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The effect of filgrastim products on the development of abnormal cytogenetics and the effect of continued filgrastim administration in patients with abnormal cytogenetics or MDS are unknown.
Anaemia in kidney disease: harnessing hypoxia responses for therapy.
Hemoglobin should be measured twice weekly for 2 to 6 weeks following dose increases.
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Erythropoietin Dose and Mortality in Hemodialysis Patients: Marginal Structural Model to Examine Causality.
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
In an examination of off-label prescribing of 160 common drugs, off-label use was also found to account for 21% of all prescriptions, and most off-label drug uses (73%) were shown to have little or no scientific support.
Figure 3 Percentage of Erythropoietic Cells in Bone Marrow Smears before and after Three Months of Erythropoietin Therapy.
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Challenge of Effectively Using Erythropoiesis-Stimulating Agents and Intravenous Iron.
Because people with certain myelodysplastic syndromes have low white blood cell counts, they're subject to recurrent, and often serious, infections.
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It is not yet known whether epoetin alfa is more effective than a placebo in treating anemia in patients receiving chemotherapy.
All this has already been accomplished by the original manufacturer, and was subsequently reflected in the brand-name drug price.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Side effects of chemotherapy depend on the particular drugs taken and the dosage or regimen.
If options for switching HIV treatment to a less hepatotoxic regimen are limited due to significant HIV resistance, for example, the decision to initiate treatment for HCV should be reassessed.
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By April 2011, three phase III trials for RA had reported positive results.
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Minimally important differences on the Functional Assessment of Cancer Therapy-Breast (FACT-B) scale: Results from ECOG Study 1193.
Hand care products, including plain (non-antimicrobial) soap and antiseptic products, can become contaminated or support the growth of microorganisms.
Med Lett Drugs Ther.
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For example, the presence of B symptoms and “bulky” (large mass) tumors are treated usually indicates a more aggressive treatment approach.
Patients with relapsed or progressive HD are often treated with high-dose chemotherapy followed by stem cell transplantation procedures.
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Few studies of people undergoing cancer treatment have addressed the issue of fatigue as a result of the emotional distress associated with undergoing a diagnostic evaluation for cancer and the effects of medical and surgical procedures used for that evaluation and for initial treatment.
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For stage III disease, chemotherapy, often with radiation, is a standard treatment.
C-infected renal transplant recipients receiving antiviral therapy.
Blood Stem Cell Support Drugs: Filgrastim (Neupogen); Epoetin ( Epogen, Procrit).
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Disease-, treatment-, and condition-specific scales, and the non-cancer specific scales (e.
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Anemia is a predictor of graft loss but not cardiovascular events and all-cause mortality in renal transplant recipients: follow-up data from the ALERT study.
As such, biosimilar mAb products should be tested for similarity of product quality attributes compared with the originator product before continuing with in vitro and in vivo comparability exercises.
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These observations suggest that TSAT and ferritin modify the observed Hb response to a change in ESA dose.
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